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Direct arene C-H fluorination with (18)F(−) via organic photoredox catalysis
Positron emission tomography (PET) plays key roles in drug discovery and development, as well as medical imaging. However, there is a dearth of efficient and simple radiolabeling methods for aromatic C–H bonds, which limits advancements in PET radiotracer development. Here, we disclose a mild method...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6680023/ https://ncbi.nlm.nih.gov/pubmed/31221856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav7019 |
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