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Reengineering a Reversible Covalent-Bonding Assembly to Optically Detect ee in β-Chiral Primary Alcohols

The use of parallel synthesis protocols for asymmetric reaction discovery has increased the need for new methods to rapidly determine enantiomeric excess (ee) values. Most chirality sensing is performed on stereocenters that are α (i.e., proximal) to the target functional group. Finding a general ap...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem
Hauptverfasser: Minus, Matthew B., Featherston, Aaron L., Choi, Sooyun, King, Sam C., Miller, Scott J., Anslyn, Eric V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774303/
https://ncbi.nlm.nih.gov/pubmed/33392417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chempr.2019.10.003
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