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Reengineering a Reversible Covalent-Bonding Assembly to Optically Detect ee in β-Chiral Primary Alcohols

The use of parallel synthesis protocols for asymmetric reaction discovery has increased the need for new methods to rapidly determine enantiomeric excess (ee) values. Most chirality sensing is performed on stereocenters that are α (i.e., proximal) to the target functional group. Finding a general ap...

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Detalhes bibliográficos
Publicado no:Chem
Main Authors: Minus, Matthew B., Featherston, Aaron L., Choi, Sooyun, King, Sam C., Miller, Scott J., Anslyn, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774303/
https://ncbi.nlm.nih.gov/pubmed/33392417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chempr.2019.10.003
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