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ZG16 regulates PD-L1 expression and promotes local immunity in colon cancer

CRC is a heterogeneous disease due to global molecular alterations, including mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H). Immunotherapy has achieved durable responses in a subset of patients with dMMR-MSI-H metastatic CRC. It has been showed that Loss of ZG16 is hig...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Meng, Hui, Ding, Yi, Liu, Enjie, Li, Wencai, Wang, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773682/
https://ncbi.nlm.nih.gov/pubmed/33360840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.101003
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