Romidepsin (FK228) regulates the expression of the immune checkpoint ligand PD-L1 and suppresses cellular immune functions in colon cancer

Romidepsin (FK228), a histone deacetylase inhibitor (HDACi), has anti-tumor effects against several types of solid tumors. Studies have suggested that HDACi could upregulate PD-L1 expression in tumor cells and change the state of anti-tumor immune responses in vivo. However, the influence of enhance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Immunol Immunother
Egile Nagusiak: Shi, Yehui, Fu, Ying, Zhang, Xin, Zhao, Gang, Yao, Yuan, Guo, Yan, Ma, Gang, Bai, Shuai, Li, Hui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838139/
https://ncbi.nlm.nih.gov/pubmed/32632663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02653-1
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