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Immune MAL2-practice: breast cancer immunoevasion via MHC class I degradation

The success of tumor immunotherapy, while partial, confirms the existence and importance of tumor immunosurveillance. CD8(+) T cell recognition of tumor-specific peptides bound to MHC class I (MHC-I) molecules is central to this process. In this issue of the JCI, Fang, Wang, et al. describe a unique...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Dersh, Devin, Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773378/
https://ncbi.nlm.nih.gov/pubmed/33393509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI144344
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