Varied Role of Ubiquitylation in Generating MHC Class I Peptide Ligands(,)

CD8(+) T cell immunosurveillance is based on recognizing oligopeptides presented by MHC class I molecules. Despite decades of study, the importance of protein ubiquitylation to peptide generation remains uncertain. Here, we examine the ability of MLN7243, a recently described ubiquitin activating en...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wei, Jiajie, Zanker, Damien, Di Carluccio, Anthony R., Smelkinson, Margery G., Takeda, Kazuyo, Seedhom, Mina O., Dersh, Devin, Gibbs, James S., Yang, Ning, Jadhav, Ajit, Chen, Weisan, Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426817/
https://ncbi.nlm.nih.gov/pubmed/28363906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602122
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