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A SIINFEKL-Based System to Measure MHC Class I Antigen Presentation Efficiency and Kinetics

Antigen presentation by classical MHC class I molecules to CD8+ T cells is a central aspect of the adaptive immune response. Here, we describe methods to monitor antigen presentation using the model ovalbumin K(b)-binding peptide, SIINFEKL. SIINFEKL genetically incorporated into viral or cellular so...

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Publicado en:Methods Mol Biol
Main Authors: Dersh, Devin, Yewdell, Jonathan W., Wei, Jiajie
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661116/
https://ncbi.nlm.nih.gov/pubmed/31147936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9450-2_9
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