Intrathecal catheter implantation decreases cerebrospinal fluid dynamics in cynomolgus monkeys

A detailed understanding of the CSF dynamics is needed for design and optimization of intrathecal drug delivery devices, drugs, and protocols. Preclinical research using large-animal models is important to help define drug pharmacokinetics-pharmacodynamics and safety. In this study, we investigated...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Udgivet i:	PLoS One
Main Authors:	Khani, Mohammadreza, Fu, Audrey Q., Pluid, Joshua, Gibbs, Christina P., Oshinski, John N., Xing, Tao, Stewart, Gregory R., Zeller, Jillynne R., Martin, Bryn A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2020
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7773283/ https://ncbi.nlm.nih.gov/pubmed/33378399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244090
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Intrathecal catheter implantation decreases cerebrospinal fluid dynamics in cynomolgus monkeys

Lignende værker