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DACH1 mutation frequency in endometrial cancer is associated with high tumor mutation burden

OBJECTIVE: DACH1 is a transcriptional repressor and tumor suppressor gene frequently mutated in melanoma, bladder, and prostate cancer. Loss of DACH1 expression is associated with poor prognostic features and reduced overall survival in uterine cancer. In this study, we utilized the Oncology Researc...

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Publicat a:PLoS One
Autors principals: Riggs, McKayla J., Lin, Nan, Wang, Chi, Piecoro, Dava W., Miller, Rachel W., Hampton, Oliver A., Rao, Mahadev, Ueland, Frederick R., Kolesar, Jill M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773279/
https://ncbi.nlm.nih.gov/pubmed/33378353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244558
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