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DACH1 mutation frequency in endometrial cancer is associated with high tumor mutation burden

OBJECTIVE: DACH1 is a transcriptional repressor and tumor suppressor gene frequently mutated in melanoma, bladder, and prostate cancer. Loss of DACH1 expression is associated with poor prognostic features and reduced overall survival in uterine cancer. In this study, we utilized the Oncology Researc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Riggs, McKayla J., Lin, Nan, Wang, Chi, Piecoro, Dava W., Miller, Rachel W., Hampton, Oliver A., Rao, Mahadev, Ueland, Frederick R., Kolesar, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773279/
https://ncbi.nlm.nih.gov/pubmed/33378353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244558
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