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Ah Receptor Ligands and Their Impacts on Gut Resilience: Structure-Activity Effects

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and structurally related halogenated aromatics modulate gene expression and induce biochemical and toxic responses that are mediated by initial binding to the aryl hydrocarbon receptor (AhR). The AhR also binds structurally diverse compound includin...

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Bibliografske podrobnosti
izdano v:Crit Rev Toxicol
Main Authors: Safe, Stephen, Jayaraman, Arul, Chapkin, Robert S.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773274/
https://ncbi.nlm.nih.gov/pubmed/32597352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10408444.2020.1773759
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