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Ah Receptor Ligands and Their Impacts on Gut Resilience: Structure-Activity Effects

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and structurally related halogenated aromatics modulate gene expression and induce biochemical and toxic responses that are mediated by initial binding to the aryl hydrocarbon receptor (AhR). The AhR also binds structurally diverse compound includin...

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Bibliographische Detailangaben
Veröffentlicht in:Crit Rev Toxicol
Hauptverfasser: Safe, Stephen, Jayaraman, Arul, Chapkin, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773274/
https://ncbi.nlm.nih.gov/pubmed/32597352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10408444.2020.1773759
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