Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells

Noncoding RNAs, such as long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), regulate gene expression in many physiological and pathological processes, including drug metabolism. Drug metabolizing enzymes (DMEs) are critical components in drug-induced liver toxicity. In this study, we used human he...

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Bibliografiske detaljer
Udgivet i:Arch Toxicol
Main Authors: Li, Dongying, Wu, Leihong, Knox, Bridgett, Chen, Si, Tolleson, William H., Liu, Fang, Yu, Dianke, Guo, Lei, Tong, Weida, Ning, Baitang
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773225/
https://ncbi.nlm.nih.gov/pubmed/32222775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02706-5
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