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Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towards neuronal and glial cells
For some complex toxicological endpoints, chemical safety assessment has conventionally relied on animal testing. Apart from the ethical issues, also scientific considerations have been raised concerning the traditional approach, highlighting the importance for considering real life exposure scenari...
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| Veröffentlicht in: | Reprod Toxicol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Pergamon In Cooperation With The Reproductive Toxicology Center
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7772889/ https://ncbi.nlm.nih.gov/pubmed/33011216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2020.09.010 |
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