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Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towards neuronal and glial cells

For some complex toxicological endpoints, chemical safety assessment has conventionally relied on animal testing. Apart from the ethical issues, also scientific considerations have been raised concerning the traditional approach, highlighting the importance for considering real life exposure scenari...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Reprod Toxicol
Egile Nagusiak: Di Consiglio, Emma, Pistollato, Francesca, Mendoza-De Gyves, Emilio, Bal-Price, Anna, Testai, Emanuela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Pergamon In Cooperation With The Reproductive Toxicology Center 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772889/
https://ncbi.nlm.nih.gov/pubmed/33011216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2020.09.010
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