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The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin
Colibactin induces DNA damage in mammalian cells and has been linked to the virulence of Escherichia coli and the promotion of colorectal cancer (CRC). By looking for mutants attenuated in the promoter activity of clbB encoding one of the key enzymes for the production of colibactin, we found that a...
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| Veröffentlicht in: | mSphere |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7771237/ https://ncbi.nlm.nih.gov/pubmed/33328353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01195-20 |
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