The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin

Colibactin induces DNA damage in mammalian cells and has been linked to the virulence of Escherichia coli and the promotion of colorectal cancer (CRC). By looking for mutants attenuated in the promoter activity of clbB encoding one of the key enzymes for the production of colibactin, we found that a...

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Xehetasun bibliografikoak
Argitaratua izan da:mSphere
Egile Nagusiak: Tang-Fichaux, Min, Chagneau, Camille V., Bossuet-Greif, Nadège, Nougayrède, Jean-Philippe, Oswald, Éric, Branchu, Priscilla
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771237/
https://ncbi.nlm.nih.gov/pubmed/33328353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01195-20
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