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Mapping the Role of AcrAB-TolC Efflux Pumps in the Evolution of Antibiotic Resistance Reveals Near-MIC Treatments Facilitate Resistance Acquisition

Antibiotic resistance has become a major public health concern as bacteria evolve to evade drugs, leading to recurring infections and a decrease in antibiotic efficacy. Systematic efforts have revealed mechanisms involved in resistance. Yet, in many cases, how these specific mechanisms accelerate or...

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Veröffentlicht in:mSphere
Hauptverfasser: Langevin, Ariel M., El Meouche, Imane, Dunlop, Mary J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771234/
https://ncbi.nlm.nih.gov/pubmed/33328350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01056-20
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