Insulin-stimulated glucose uptake partly relies on p21-activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle

The group I p21-activated kinase (PAK) isoforms PAK1 and PAK2 are activated in response to insulin in skeletal muscle and PAK1/2 signalling is impaired in insulin-resistant mouse and human skeletal muscle. Interestingly, PAK1 has been suggested to be required for insulin-stimulated GLUT4 translocati...

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Publicado en:J Physiol
Autores principales: Møller, Lisbeth L. V., Jaurji, Merna, Kjøbsted, Rasmus, Joseph, Giselle A., Madsen, Agnete B., Knudsen, Jonas R., Lundsgaard, Anne-Marie, Andersen, Nicoline R., Schjerling, Peter, Jensen, Thomas E., Krauss, Robert S., Richter, Erik A., Sylow, Lykke
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771197/
https://ncbi.nlm.nih.gov/pubmed/32844438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280294
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