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Insulin-stimulated glucose uptake partly relies on p21-activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
The group I p21-activated kinase (PAK) isoforms PAK1 and PAK2 are activated in response to insulin in skeletal muscle and PAK1/2 signalling is impaired in insulin-resistant mouse and human skeletal muscle. Interestingly, PAK1 has been suggested to be required for insulin-stimulated GLUT4 translocati...
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| Udgivet i: | J Physiol |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7771197/ https://ncbi.nlm.nih.gov/pubmed/32844438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP280294 |
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