MFSD12 mediates the import of cysteine into melanosomes and lysosomes

Dozens of genes contribute to the vast variation in human pigmentation. Many of these encode proteins that localize to the melanosome, the lysosome-related organelle that synthesizes pigment, but have unclear functions (1,2). Here, we describe the MelanoIP method for rapidly isolating melanosomes an...

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Pubblicato in:Nature
Autori principali: Adelmann, Charles H., Traunbauer, Anna K., Chen, Brandon, Condon, Kendall J., Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A., Sabatini, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770032/
https://ncbi.nlm.nih.gov/pubmed/33208952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2937-x
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