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MFSD12 mediates the import of cysteine into melanosomes and lysosomes

Dozens of genes contribute to the vast variation in human pigmentation. Many of these encode proteins that localize to the melanosome, the lysosome-related organelle that synthesizes pigment, but have unclear functions (1,2). Here, we describe the MelanoIP method for rapidly isolating melanosomes an...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Adelmann, Charles H., Traunbauer, Anna K., Chen, Brandon, Condon, Kendall J., Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A., Sabatini, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770032/
https://ncbi.nlm.nih.gov/pubmed/33208952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2937-x
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