Astrocyte HIV-1 Tat Differentially Modulates Behavior and Brain MMP/TIMP Balance During Short and Prolonged Induction in Transgenic Mice

Despite effective antiretroviral therapy (ART), mild forms of HIV-associated neurocognitive disorders (HAND) continue to afflict approximately half of all people living with HIV (PLWH). As PLWH age, HIV-associated inflammation perturbs the balance between brain matrix metalloproteinases (MMPs) and t...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Joshi, Chaitanya R., Stacy, Satomi, Sumien, Nathalie, Ghorpade, Anuja, Borgmann, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769877/
https://ncbi.nlm.nih.gov/pubmed/33384653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.593188
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