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Novel Role of TGF-β in Differential Astrocyte-TIMP-1 Regulation: Implications for HIV-1-Dementia and Neuroinflammation

Astrocyte production of tissue inhibitor of metalloproteinase (TIMP)-1 is important in central nervous system (CNS) homeostasis and inflammatory diseases such as HIV-1-associated dementia (HAD). TIMPs and matrix metalloproteinases (MMPs) regulate the remodeling of the extracellular matrix. An imbala...

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Autors principals: Dhar, Alok, Gardner, Jessica, Borgmann, Kathleen, Wu, Li, Ghorpade, Anuja
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820372/
https://ncbi.nlm.nih.gov/pubmed/16496359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.20787
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