HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation

Gene expression programs determine cell fate in embryonic development and their dysregulation results in disease. Transcription factors (TFs) control gene expression by binding to enhancers, but how TFs select and activate their target enhancers is still unclear. HOX TFs share conserved homeodomains...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Genet
Κύριοι συγγραφείς: Bridoux, Laure, Zarrineh, Peyman, Mallen, Joshua, Phuycharoen, Mike, Latorre, Victor, Ladam, Frank, Losa, Marta, Baker, Syed Murtuza, Sagerstrom, Charles, Mace, Kimberly A., Rattray, Magnus, Bobola, Nicoletta
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2020
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769617/
https://ncbi.nlm.nih.gov/pubmed/33315856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009162
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