טוען...

HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation

Gene expression programs determine cell fate in embryonic development and their dysregulation results in disease. Transcription factors (TFs) control gene expression by binding to enhancers, but how TFs select and activate their target enhancers is still unclear. HOX TFs share conserved homeodomains...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Genet
Main Authors: Bridoux, Laure, Zarrineh, Peyman, Mallen, Joshua, Phuycharoen, Mike, Latorre, Victor, Ladam, Frank, Losa, Marta, Baker, Syed Murtuza, Sagerstrom, Charles, Mace, Kimberly A., Rattray, Magnus, Bobola, Nicoletta
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769617/
https://ncbi.nlm.nih.gov/pubmed/33315856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009162
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