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Uncovering tissue-specific binding features from differential deep learning
Transcription factors (TFs) can bind DNA in a cooperative manner, enabling a mutual increase in occupancy. Through this type of interaction, alternative binding sites can be preferentially bound in different tissues to regulate tissue-specific expression programmes. Recently, deep learning models ha...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049686/ https://ncbi.nlm.nih.gov/pubmed/31974574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa009 |
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