Uncovering tissue-specific binding features from differential deep learning

Transcription factors (TFs) can bind DNA in a cooperative manner, enabling a mutual increase in occupancy. Through this type of interaction, alternative binding sites can be preferentially bound in different tissues to regulate tissue-specific expression programmes. Recently, deep learning models ha...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Phuycharoen, Mike, Zarrineh, Peyman, Bridoux, Laure, Amin, Shilu, Losa, Marta, Chen, Ke, Bobola, Nicoletta, Rattray, Magnus
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049686/
https://ncbi.nlm.nih.gov/pubmed/31974574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa009
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