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Meiotic susceptibility for induction of sperm with chromosomal aberrations in patients receiving combination chemotherapy for Hodgkin lymphoma

Improvements in survival rates with gonad-sparing protocols for childhood and adolescence cancer have increased the optimism of survivors to become parents after treatment. Findings in rodents indicate that chromosomal aberrations can be induced in male germ cells by genotoxic exposures and transmit...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Frias, Sara, Van Hummelen, Paul, Meistrich, Marvin L., Wyrobek, Andrew J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769287/
https://ncbi.nlm.nih.gov/pubmed/33370316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242218
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