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Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations
Male and female germ cells can transmit genetic defects that lead to pregnancy loss, infant mortality, birth defects, and genetic diseases in offspring; however, the parental origins of transmitted defects are not random, with de novo mutations and chromosomal structural aberrations transmitted pred...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077046/ https://ncbi.nlm.nih.gov/pubmed/17978187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705257104 |
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