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Meiotic susceptibility for induction of sperm with chromosomal aberrations in patients receiving combination chemotherapy for Hodgkin lymphoma

Improvements in survival rates with gonad-sparing protocols for childhood and adolescence cancer have increased the optimism of survivors to become parents after treatment. Findings in rodents indicate that chromosomal aberrations can be induced in male germ cells by genotoxic exposures and transmit...

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Udgivet i:PLoS One
Main Authors: Frias, Sara, Van Hummelen, Paul, Meistrich, Marvin L., Wyrobek, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769287/
https://ncbi.nlm.nih.gov/pubmed/33370316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242218
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