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Regulation of neovasculogenesis in co-cultures of aortic adventitial fibroblasts and microvascular endothelial cells by cell-cell interactions and TGF-β/ALK5 signaling

Adventitial fibroblasts (AFs) are critical mediators of vascular remodeling. However, the contributions of AFs towards development of vasculature and the specific mechanisms by which these cells regulate physiological expansion of the vasa vasorum, the specialized microvasculature that supplies nutr...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Scott, Rebecca A., Fowler, Eric W., Jia, Xinqiao, Kiick, Kristi L., Akins, Robert E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769260/
https://ncbi.nlm.nih.gov/pubmed/33370415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244243
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