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Aortic Adventitial Fibroblast Sensitivity to Mitogen Activated Protein Kinase Inhibitors Depends on Substrate Stiffness

Adventitial fibroblasts (AFs) are key determinants of arterial function and critical mediators of arterial disease progression. The effects of altered stiffness, particularly those observed across individuals during normal vascular function, and the mechanisms by which AFs respond to altered stiffne...

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Detalles Bibliográficos
Publicado en:Biomaterials
Main Authors: Scott, Rebecca A., Kharkar, Prathamesh M., Kiick, Kristi L., Akins, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554066/
https://ncbi.nlm.nih.gov/pubmed/28527302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.05.010
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