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Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction

Endoglin is a transmembrane accessory receptor for transforming growth factor-β (TGF-β) that is predominantly expressed on proliferating endothelial cells in culture and on angiogenic blood vessels in vivo. Endoglin, as well as other TGF-β signalling components, is essential during angiogenesis. Mut...

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Autors principals: Lebrin, Franck, Goumans, Marie-José, Jonker, Leon, Carvalho, Rita L C, Valdimarsdottir, Gudrun, Thorikay, Midory, Mummery, Christine, Arthur, Helen M, Dijke, Peter ten
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC524335/
https://ncbi.nlm.nih.gov/pubmed/15385967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600386
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