Suppression of Urokinase-Type Plasminogen Activator Receptor by Docosahexaenoic Acid Mediated by Heme Oxygenase-1 in 12-O-Tetradecanoylphorbol-13-Acetate-Induced Human Endothelial Cells

Urokinase-type plasminogen activator receptor (uPAR) plays a crucial role in inflammation and tumor metastasis. Docosahexaenoic acid (DHA), a representative omega-3 polyunsaturated fatty acid, has been shown to exhibit anti-inflammatory and anti-tumor properties. However, the mechanism by which DHA...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lian, Sen, Li, Shinan, Sah, Dhiraj Kumar, Kim, Nam Ho, Lakshmanan, Vinoth‐Kumar, Jung, Young Do
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768974/
https://ncbi.nlm.nih.gov/pubmed/33381031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.577302
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