Docosahexaenoic Acid Inhibits Tumor Promoter-Induced Urokinase-Type Plasminogen Activator Receptor by Suppressing PKCδ- and MAPKs-Mediated Pathways in ECV304 Human Endothelial Cells

The overexpression of urokinase-type plasminogen activator receptor (uPAR) is associated with inflammation and virtually all human cancers. Despite the fact that docosahexaenoic acid (DHA) has been reported to possess anti-inflammatory and anti-tumor properties, the negative regulation of uPAR by DH...

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Foilsithe in:PLoS One
Main Authors: Lian, Sen, Xia, Yong, Nguyen, Thi Thinh, Ung, Trong Thuan, Yoon, Hyun Joong, Kim, Nam Ho, Kim, Kyung Keun, Jung, Young Do
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031411/
https://ncbi.nlm.nih.gov/pubmed/27654969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163395
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