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Benchmark of Generic Shapes for Macrocycles

[Image: see text] Macrocycles target proteins that are otherwise considered undruggable because of a lack of hydrophobic cavities and the presence of extended featureless surfaces. Increasing efforts by computational chemists have developed effective software to overcome the restrictions of torsiona...

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Detalles Bibliográficos
Publicado en:J Chem Inf Model
Main Authors: Reyes Romero, Atilio, Ruiz-Moreno, Angel Jonathan, Groves, Matthew R., Velasco-Velázquez, Marco, Dömling, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768607/
https://ncbi.nlm.nih.gov/pubmed/33270455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c01038
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