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Differential Sex-Dependent Regulation of the Alveolar Macrophage miRNome of SP-A2 and co-ex (SP-A1/SP-A2) and Sex Differences Attenuation after 18 h of Ozone Exposure

Background: Human SP-A1 and SP-A2, encoded by SFTPA1 and SFTPA2, and their genetic variants differentially impact alveolar macrophage (AM) functions and regulation, including the miRNome. We investigated whether miRNome differences previously observed between AM from SP-A2 and SP-A1/SP-A2 mice are d...

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Foilsithe in:Antioxidants (Basel)
Main Authors: Thorenoor, Nithyananda, Phelps, David S., Floros, Joanna
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768498/
https://ncbi.nlm.nih.gov/pubmed/33260937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121190
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