Multicenter, Randomized, Phase III Trial of Neoadjuvant Chemoradiation With Capecitabine and Irinotecan Guided by UGT1A1 Status in Patients With Locally Advanced Rectal Cancer

Differentiating the irinotecan dose on the basis of the uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) genotype improves the pathologic complete response (pCR) rate. In this study, we further investigated preoperative irinotecan combined with capecitabine-based chemoradiotherapy for locall...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Oncol
Egile Nagusiak: Zhu, Ji, Liu, Anwen, Sun, Xinchen, Liu, Luying, Zhu, Yaqun, Zhang, Tao, Jia, Jianhui, Tan, Shisheng, Wu, Junxin, Wang, Xin, Zhou, Juying, Yang, Jialin, Zhang, Chen, Zhang, Hongyan, Zhao, Yuanyuan, Cai, Gang, Zhang, Wei, Xia, Fan, Wan, Juefeng, Zhang, Hui, Shen, Lijun, Cai, SanJun, Zhang, Zhen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Clinical Oncology 2020
Gaiak:
ORIGINAL REPORTS
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768334/
https://ncbi.nlm.nih.gov/pubmed/33119477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.20.01932
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