Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK–driven lymphomagenesis

Malignant transformation depends on genetic and epigenetic events that result in a burst of deregulated gene expression and chromatin changes. To dissect the sequence of events in this process, we used a T-cell–specific lymphoma model based on the human oncogenic nucleophosmin-anaplastic lymphoma ki...

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Publicat a:Life Sci Alliance
Autors principals: Redl, Elisa, Sheibani-Tezerji, Raheleh, Cardona, Crhistian de Jesus, Hamminger, Patricia, Timelthaler, Gerald, Hassler, Melanie Rosalia, Zrimšek, Maša, Lagger, Sabine, Dillinger, Thomas, Hofbauer, Lorena, Draganić, Kristina, Tiefenbacher, Andreas, Kothmayer, Michael, Dietz, Charles H, Ramsahoye, Bernard H, Kenner, Lukas, Bock, Christoph, Seiser, Christian, Ellmeier, Wilfried, Schweikert, Gabriele, Egger, Gerda
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768196/
https://ncbi.nlm.nih.gov/pubmed/33310759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000794
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