Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK–driven lymphomagenesis

Malignant transformation depends on genetic and epigenetic events that result in a burst of deregulated gene expression and chromatin changes. To dissect the sequence of events in this process, we used a T-cell–specific lymphoma model based on the human oncogenic nucleophosmin-anaplastic lymphoma ki...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Redl, Elisa, Sheibani-Tezerji, Raheleh, Cardona, Crhistian de Jesus, Hamminger, Patricia, Timelthaler, Gerald, Hassler, Melanie Rosalia, Zrimšek, Maša, Lagger, Sabine, Dillinger, Thomas, Hofbauer, Lorena, Draganić, Kristina, Tiefenbacher, Andreas, Kothmayer, Michael, Dietz, Charles H, Ramsahoye, Bernard H, Kenner, Lukas, Bock, Christoph, Seiser, Christian, Ellmeier, Wilfried, Schweikert, Gabriele, Egger, Gerda
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768196/
https://ncbi.nlm.nih.gov/pubmed/33310759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000794
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