Dibenzazepine Attenuates Against Cisplatin-Induced Nephrotoxicity in Rats: Involvement of NOTCH Pathway

Cisplatin is one of the standard anti-cancer agents that are used to treat variety of solid tumors. Nevertheless, due to the accumulation of cisplatin in the renal epithelial cells, nephrotoxicity was found to be the main side effect that limits its clinical use. The current study was conducted to a...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Abd El-Rhman, Rana H., El-Naga, Reem N., Gad, Amany M., Tadros, Mariane G., Hassaneen, Sherifa K.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768080/
https://ncbi.nlm.nih.gov/pubmed/33381027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.567852
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