The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration

Sorsby Fundus Dystrophy (SFD) is a rare inherited autosomal dominant macular degeneration caused by specific mutations in TIMP3. Patients with SFD present with pathophysiology similar to the more common Age-related Macular Degeneration (AMD) and loss of vision due to both choroidal neovascularizatio...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Wolk, Alyson, Upadhyay, Mala, Ali, Mariya, Suh, Jason, Stoehr, Heidi, Bonilha, Vera L., Anand-Apte, Bela
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767753/
https://ncbi.nlm.nih.gov/pubmed/32828705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101681
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