Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice

Tristetraprolin (TTP), an mRNA binding and decaying protein, plays a significant role in controlling inflammation by decaying mRNAs encoding inflammatory cytokines such as TNFalpha. We aimed to test a hypothesis that TTP in bone marrow (BM) cells regulates atherogenesis by modulating inflammation an...

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Detaylı Bibliyografya
Yayımlandı:Redox Biol
Asıl Yazarlar: Saaoud, Fatma, Wang, Junfeng, Iwanowycz, Stephen, Wang, Yuzhen, Altomare, Diego, Shao, Ying, Liu, Jianguo, Blackshear, Perry J., Lessner, Susan M., Murphy, E. Angela, Wang, Hong, Yang, Xiaofeng, Fan, Daping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Articles from the Special Issue on Redox Signalling and Cardiovascular Disease; Edited by Christopher Kevil and Yabing Chen
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767740/
https://ncbi.nlm.nih.gov/pubmed/32591281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101609
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