The Antimalarial Compound Atovaquone Inhibits Zika and Dengue Virus Infection by Blocking E Protein-Mediated Membrane Fusion

Flaviviruses bear class II fusion proteins as their envelope (E) proteins. Here, we describe the development of an in vitro quantitative mosquito-cell-based membrane-fusion assay for the E protein using dual split proteins (DSPs). The assay does not involve the use of live viruses and allows the ana...

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Publicado no:Viruses
Main Authors: Yamamoto, Mizuki, Ichinohe, Takeshi, Watanabe, Aya, Kobayashi, Ayako, Zhang, Rui, Song, Jiping, Kawaguchi, Yasushi, Matsuda, Zene, Inoue, Jun-ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767512/
https://ncbi.nlm.nih.gov/pubmed/33371476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121475
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