Cell–cell and virus–cell fusion assay–based analyses of alanine insertion mutants in the distal α9 portion of the JRFL gp41 subunit from HIV-1

Membrane fusion is the first essential step in HIV-1 replication. The gp41 subunit of HIV-1 envelope protein (Env), a class I fusion protein, achieves membrane fusion by forming a structure called a six-helix bundle composed of N- and C-terminal heptad repeats. We have recently shown that the distal...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Yamamoto, Mizuki, Du, Qingling, Song, Jiping, Wang, Hongyun, Watanabe, Aya, Tanaka, Yuetsu, Kawaguchi, Yasushi, Inoue, Jun-ichiro, Matsuda, Zene
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Methods and Resources
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462516/
https://ncbi.nlm.nih.gov/pubmed/30737278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004579
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