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Adipocyte-Derived Leptin Promotes PAI-1-Mediated Breast Cancer Metastasis in a STAT3/miR-34a Dependent Manner

SIMPLE SUMMARY: Although adipocytes affect the metastatic behavior of cancer cells, the underlying molecular mechanisms remain largely elusive. Thereby, we sought to screen for the signaling pathways responsible for adipocyte-induced motility of breast cancer cells by employing a breast cancer cell/...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Li, Si-Jing, Wei, Xiao-Hui, Zhan, Xiao-Man, He, Jin-Yong, Zeng, Yu-Qi, Tian, Xue-Mei, Yuan, Sheng-Tao, Sun, Li
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767398/
https://ncbi.nlm.nih.gov/pubmed/33371368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123864
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