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Biased Ligands Differentially Shape the Conformation of the Extracellular Loop Region in 5-HT(2B) Receptors
G protein-coupled receptors are linked to various intracellular transducers, each pathway associated with different physiological effects. Biased ligands, capable of activating one pathway over another, are gaining attention for their therapeutic potential, as they could selectively activate benefic...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7767279/ https://ncbi.nlm.nih.gov/pubmed/33419260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249728 |
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