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Cellular Targeting of Oligonucleotides by Conjugation with Small Molecules

Drug candidates derived from oligonucleotides (ON) are receiving increased attention that is supported by the clinical approval of several ON drugs. Such therapeutic ON are designed to alter the expression levels of specific disease-related proteins, e.g., by displaying antigene, antisense, and RNA...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Hawner, Manuel, Ducho, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766908/
https://ncbi.nlm.nih.gov/pubmed/33339365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245963
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