Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity

CONTEXT: Pancreatic beta-cell glucose sensitivity is the slope of the plasma glucose-insulin secretion relationship and is a key predictor of deteriorating glucose tolerance and development of type 2 diabetes. However, there are no large-scale studies looking at the genetic determinants of beta-cell...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Deshmukh, Harshal A, Madsen, Anne Lundager, Viñuela, Ana, Have, Christian Theil, Grarup, Niels, Tura, Andrea, Mahajan, Anubha, Heggie, Alison J, Koivula, Robert W, De Masi, Federico, Tsirigos, Konstantinos K, Linneberg, Allan, Drivsholm, Thomas, Pedersen, Oluf, Sørensen, Thorkild I A, Astrup, Arne, Gjesing, Anette A P, Pavo, Imre, Wood, Andrew R, Ruetten, Hartmut, Jones, Angus G, Koopman, Anitra D M, Cederberg, Henna, Rutters, Femke, Ridderstrale, Martin, Laakso, Markku, McCarthy, Mark I, Frayling, Tim M, Ferrannini, Ele, Franks, Paul W, Pearson, Ewan R, Mari, Andrea, Hansen, Torben, Walker, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765651/
https://ncbi.nlm.nih.gov/pubmed/32944759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa653
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