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Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity
BACKGROUND: Mutations in the genes encoding leptin (LEP), the leptin receptor (LEPR), and the melanocortin 4 receptor (MC4R) are known to cause severe early-onset childhood obesity. The aim of the current study was to examine the prevalence of damaging LEP, LEPR, and MC4R mutations in Pakistani fami...
Shranjeno v:
| izdano v: | BMC Med Genet |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6238292/ https://ncbi.nlm.nih.gov/pubmed/30442103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-018-0710-x |
| Oznake: |
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