Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants

BACKGROUND: Based on the association of common GLIS3 variants with various forms of diabetes and the biological role of GLIS3 in beta-cells, we sequenced GLIS3 in non-diabetic and diabetic Danes to investigate the effect of rare missense variants on glucose metabolism. METHODS: We sequenced 53 patie...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sun, Jihua, Have, Christian Theil, Hollensted, Mette, Grarup, Niels, Linneberg, Allan, Pedersen, Oluf, Nielsen, Jens Steen, Rungby, Jørgen, Christensen, Cramer, Brandslund, Ivan, Kristiansen, Karsten, Jun, Wang, Hansen, Torben, Gjesing, Anette P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695102/
https://ncbi.nlm.nih.gov/pubmed/31415576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220805
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires