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Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants
BACKGROUND: Based on the association of common GLIS3 variants with various forms of diabetes and the biological role of GLIS3 in beta-cells, we sequenced GLIS3 in non-diabetic and diabetic Danes to investigate the effect of rare missense variants on glucose metabolism. METHODS: We sequenced 53 patie...
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| I publikationen: | PLoS One |
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| Huvudupphovsmän: | , , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6695102/ https://ncbi.nlm.nih.gov/pubmed/31415576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220805 |
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